Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata
نویسندگان
چکیده
Kalanchoe pinnata leaves are used in South Asia as a natural kidney stone treatment. In vitro studies were conducted supersaturated and artificial urine solutions to evaluate the antiurolithic properties of K. leaf extract on calcium oxalate monohydrate (COM) surgically extracted stones. Key organic acids present plant also examined investigate inhibition formation. Crystals harvested from dissolution experiments characterized by mass change, Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), redox titrations, conductivity measurements. significantly inhibited crystal growth mechanisms depending concentration supported dissolution. Crystal was 41 15 wt%, respectively, COM decreased 30 18 wt% after five washes. Active compounds identified malic, p-hydroxybenzoic, syringic, caffeic acids, each demonstrated 2.70 4.65 inhibition, which cumulatively accounts for 15% observed synthetic urine. This preliminary study demonstrates that acid content is crucial component activity. words: Kidney stones, monohydrate, Kalonchoe leaves, effects, Ayurvedic.
منابع مشابه
In-vitro Antiurolithiatic Activity of Kalanchoe pinnata Extract
Background: Upto date, the scientific documentation regarding in-vivo antiurolithiatic activity of Kalanchoe pinnata has been reported, although it has not reported for in-vitro antiurolithiatic activity up till now. Objective: To explore anti-urolithiatic activities of Kalanchoe pinnata leaves extract by utilizing different in-vitro models. To investigate the inhibitory effect of extract on in...
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ژورنال
عنوان ژورنال: Journal of Medicinal Plants Research
سال: 2023
ISSN: ['1996-0875']
DOI: https://doi.org/10.5897/jmpr2023.7296